Description
Herpes Simplex Virus is a common pathogen and its primary infection is usually asymptomatic. There are two immunologically distinct types of HSV: Type 1 and Type 2. HSV 1 is generally associated with oral infection and lesions above the waist, and HSV 2 is associated with genital infections and lesions below the waist. Clinical cases primarily are 1) eczema herpeticum with eczematous skin changes with numerous lesions, 2) Gingivo-stomatitis and 3) Herpes sepsis, almost only found in newly born of premature infants. The antibodies present to HSV 1 may be of the IgA, IgM and IgG isotypes. The physiological function of IgA and its clinical implication is still unclear. The Creative Diagnostics ELISA HSV 1 IgA is an accurate and sensitive serologic method to detect HSV 1 antibody IgA isotype